右美托咪定
医学
镇静
麻醉
镇静剂
重症监护
心动过缓
异丙酚
插管
重症监护医学
心率
血压
放射科
作者
Ehab Farag,Maged Argalious,Alaa Abd‐Elsayed,Zeyd Ebrahim,D. John Doyle
标识
DOI:10.2174/138161212803832272
摘要
The alpha-2 agonist dexmedetomidine is being increasingly used for sedation and as an adjunctive agent during general and regional anesthesia. It is used in a number of procedures and clinical settings including neuroanesthesia, vascular surgery, gastrointestinal endoscopy, fiberoptic intubation, and pediatric anesthesia. The drug is also considered a nearly ideal sedative agent in the intensive care setting. However, the drug frequently produces hypotension and bradycardia, and also decreases cerebral blood flow without concomitantly decreasing the cerebral metabolic rate for oxygen. This review discusses recent advances in the use of dexmedetomidine in anesthesia and intensive care settings, as well as discuss potential problems with its use.
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