CTCA Prior to Invasive Coronary Angiography in Patients With Previous Bypass Surgery: Patient-Related Outcomes, Imaging Resource Utilization, and Cardiac Events at 3 Years From the BYPASS-CTCA Trial

医学 心绞痛 随机对照试验 放射科 内科学 心脏病学 血管造影 冠状动脉搭桥手术 入射(几何) 动脉 心肌梗塞 物理 光学
作者
Matthew Kelham,Anne‐Marie Beirne,Krishnaraj S. Rathod,Mervyn Andiapen,Lucinda Wynne,Annastazia Learoyd,Nasim Forooghi,Rohini Ramaseshan,James Moon,Ceri Davies,Christos V. Bourantas,Andreas Baumbach,Charlotte Manisty,Andrew Wragg,Amrita Ahluwalia,Francesca Pugliese,Anthony Mathur,Daniel A. Jones
出处
期刊:Circulation-cardiovascular Interventions [Lippincott Williams & Wilkins]
被引量:1
标识
DOI:10.1161/circinterventions.124.014142
摘要

BACKGROUND: In patients with previous coronary artery bypass grafting, computed tomography cardiac angiography (CTCA) before invasive coronary angiography (ICA) was demonstrated in the BYPASS-CTCA trial (Randomized Controlled Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients) to reduce procedure time and incidence of contrast-associated acute kidney injury, with greater levels of patient satisfaction. Patient-related outcomes, utilization of further diagnostic imaging resources, and longer-term incidence of major adverse cardiac events were key secondary end points not yet reported. METHODS: Patients with prior coronary artery bypass grafting referred for ICA were randomized 1:1 to undergo CTCA before ICA or ICA alone and followed up for a median of 3 (2.2-3.4) years. Angina status was assessed using the Seattle Angina Questionnaire and overall quality of life using the EQ-5D-5L. The incidence of noninvasive imaging use and major adverse cardiac events were compared between the 2 groups. RESULTS: In all, 688 patients were randomized, 344 to CTCA+ICA and 344 to ICA only. The mean age of participants was 69.8 years, with 45% undergoing ICA for acute coronary syndromes and the remainder stable angina. At 3 months follow-up, patients in the CTCA+ICA group were more likely to be angina-free (51.7% versus 43.2%; P =0.03) with greater quality of life (EQ-5D-5L index, 81.6 versus 74.4; P =0.001), although these improvements did not persist. At 3 years follow-up, imaging resource use (35.8% versus 45.1%; odds ratio, 0.68 [95% CI, 0.50–0.92]; P =0.013) and incidence of major adverse cardiac events were lower in the CTCA+ICA group (35.8% versus 43.5%; hazard ratio, 0.73 [95% CI, 0.58–0.93]; P =0.010). CONCLUSIONS: In patients with prior coronary artery bypass grafting undergoing ICA, CTCA before ICA leads to reductions in the use of imaging resources and the rate of major cardiac events out to 3 years, but with similar patient-related outcome measures. Together with the initial findings of BYPASS-CTCA, these data are supportive of routinely undertaking a CTCA before ICA in patients with prior coronary artery bypass grafting. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03736018.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
2秒前
2秒前
量子星尘发布了新的文献求助10
3秒前
3秒前
5秒前
5秒前
6秒前
小杨完成签到 ,获得积分10
7秒前
yyz发布了新的文献求助10
8秒前
9秒前
欧耶发布了新的文献求助10
11秒前
YY张完成签到,获得积分20
11秒前
13秒前
13秒前
Joyce完成签到,获得积分10
14秒前
万能图书馆应助悦耳昊强采纳,获得10
15秒前
15秒前
天真的不尤完成签到 ,获得积分10
16秒前
悄悄睡觉完成签到 ,获得积分10
17秒前
小仙女发布了新的文献求助30
17秒前
小晓发布了新的文献求助10
17秒前
18秒前
领导范儿应助无限飞丹采纳,获得10
18秒前
美好的秋烟完成签到,获得积分20
19秒前
19秒前
幸福大白发布了新的文献求助30
20秒前
哒哒哒发布了新的文献求助10
21秒前
悦耳昊强完成签到,获得积分20
26秒前
打打应助顺利紫山采纳,获得10
27秒前
CR7应助ZONG采纳,获得20
28秒前
可爱的函函应助77采纳,获得10
28秒前
科研通AI2S应助李健采纳,获得10
28秒前
研友_VZG7GZ应助科研通管家采纳,获得10
29秒前
29秒前
大模型应助科研通管家采纳,获得30
29秒前
YamDaamCaa应助科研通管家采纳,获得30
29秒前
慕青应助科研通管家采纳,获得10
29秒前
小蘑菇应助科研通管家采纳,获得10
29秒前
Ava应助科研通管家采纳,获得10
29秒前
CipherSage应助科研通管家采纳,获得10
30秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989450
求助须知:如何正确求助?哪些是违规求助? 3531621
关于积分的说明 11254315
捐赠科研通 3270207
什么是DOI,文献DOI怎么找? 1804928
邀请新用户注册赠送积分活动 882105
科研通“疑难数据库(出版商)”最低求助积分说明 809176