Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer with PD-L1 ≥ 1 %: A subgroup analysis from the EMPOWER-Lung 3 part 2 trial
医学
化疗
肿瘤科
肺癌
内科学
肺
子群分析
荟萃分析
作者
Ana Baramidze,Tamta Makharadze,Miranda Gogishvili,Tamar Melkadze,Davit Giorgadze,Konstantin Penkov,К. К. Лактионов,Gia Nemsadze,Marina Nechaeva,Irina Rozhkova,Ewa Kalinka‐Warzocha,D. McIntyre,Javier J. Pérez,M. Kaul,Ruben G.W. Quek,Frank Seebach,Petra Rietschel,Jean‐François Pouliot
出处
期刊:Lung Cancer [Elsevier] 日期:2024-05-13卷期号:193: 107821-107821
EMPOWER-Lung 3 part 2 (NCT03409614), a double-blind, placebo-controlled phase 3 study, assessed cemiplimab (anti-programmed cell death protein 1) plus chemotherapy versus chemotherapy alone in patients with advanced non-small cell lung cancer (NSCLC) without EGFR, ALK, or ROS1 aberrations, regardless of histology or PD-L1 expression levels. We report results from subgroup analysis of patients with PD-L1 expression ≥ 1 %.