An Aneurysmal bone cyst harboring a novel ACSL4::USP6 fusion gene

The usefulness of computed tomography (CT) for measuring bone defect volume in the alveolar cleft has attracted considerable attention in recent years. Moreover, 320-row area detector CT (320-ADCT) is currently widely utilized. This technology helps to acquire smooth three-dimensional images, with a reduced exposure dose and improved image resolution, similar to those of dental cone-beam CT (CBCT). We compared the exposure dose of 320-ADCT with that of dental CBCT, and analyzed the reliability of a volumetric method for measuring bone defects in the alveolar cleft using 320-ADCT, both experimentally and clinically.We performed thermoluminescent dosimeter measurements using an anthropomorphic RANDO phantom. Additionally, we evaluated the reproducibility of the volumetric measurement method for the bone defective volume using CT images of simulated bone defects in pigs. In addition, we evaluated the inter-rater reliability of the volumetrically measured values of bone defects in 20 patients with a unilateral cleft.The exposure doses of 320-row area detector CT and CBCT were similar. The errors of volumetric values between calculated and actual bone defects created in pigs were up to 7.6%. Inter-rater reliability of the calculated volumes of bone defect was evaluated as high, according to Bland–Altman analysis.CT examination with a low exposure dose and precise analysis is feasible without the use of highly specialized dental CBCT.