抗生素
重症监护医学
抗生素耐药性
抗菌剂
医学
药品
抗药性
生物
药理学
微生物学
作者
Eva María Arroyo-Urea,Maria Lázaro-Díez,Junkal Garmendia,Fernando Herranz,Ana González-Paredes
出处
期刊:Nanomedicine
[Future Medicine]
日期:2024-01-25
卷期号:19 (4): 325-343
被引量:2
标识
DOI:10.2217/nnm-2023-0243
摘要
The global threat posed by antimicrobial resistance demands urgent action and the development of effective drugs. Lower respiratory tract infections remain the deadliest communicable disease worldwide, often challenging to treat due to the presence of bacteria that form recalcitrant biofilms. There is consensus that novel anti-infectives with reduced resistance compared with conventional antibiotics are needed, leading to extensive research on innovative antibacterial agents. This review explores the recent progress in lipid-based nanomedicines developed to counteract bacterial respiratory infections, especially those involving biofilm growth; focuses on improved drug bioavailability and targeting and highlights novel strategies to enhance treatment efficacy while emphasizing the importance of continued research in this dynamic field.
科研通智能强力驱动
Strongly Powered by AbleSci AI