Design and Analysis of Unit Cell Geometry to Improve Mechanical Properties and Surface‐to‐Volume Ratio of Used Scaffold in Treating Damaged Bone Tissue

材料科学 脚手架 生物医学工程 生物相容性 松质骨 组织工程 股骨 骨组织 多孔性 复合材料 解剖 医学 外科 冶金
作者
Mohammad Javad Khoshgoftar,Hamidreza Ansari
出处
期刊:Advanced Engineering Materials [Wiley]
被引量:1
标识
DOI:10.1002/adem.202301600
摘要

Bone tissue damage resulting from trauma, tumor, or bone infection is one of the most common problems that humans face in everyday life. Tissue engineering is a developing method for the reconstruction and repair of damaged tissues, and a scaffold should have properties such as biocompatibility, mechanical properties suitable for the type of damaged tissue, and suitable surface characteristics for better cell adhesion. This study presents a precise and practical process for designing a scaffold used in bone tissue repair, such as the femur, and the effect of unit cell geometry on the mechanical properties and surface characteristics of the scaffold is investigated. CT scan images of the human femur area were obtained, and 3D models of the cortical and cancellous parts of the femur were constructed. The outer surface of the damaged parts was designed with ideal geometry; six types of unit cells with different geometries were designed, and the changes in the Young’s modulus were determined as a function of changes in the unit cell porosity. The cubic‐star‐shaped unit cell was chosen as the suitable unit cell for the scaffold structure, with a side length of 0.88 mm and a pore size of 0.6 mm. This article is protected by copyright. All rights reserved.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
lhl发布了新的文献求助10
2秒前
2秒前
zhizhi发布了新的文献求助10
2秒前
张秋贤关注了科研通微信公众号
3秒前
4秒前
aaa发布了新的文献求助10
5秒前
林楠发布了新的文献求助10
5秒前
Hello应助解丽采纳,获得10
7秒前
healer发布了新的文献求助10
7秒前
8秒前
8秒前
9秒前
11秒前
一味地丶逞强完成签到,获得积分10
12秒前
13秒前
善学以致用应助zhizhi采纳,获得10
14秒前
kkk发布了新的文献求助10
14秒前
xujunjie完成签到,获得积分10
15秒前
舟行碧波上应助May采纳,获得10
16秒前
vv发布了新的文献求助10
16秒前
科研通AI2S应助东方天奇采纳,获得10
16秒前
晚风发布了新的文献求助10
16秒前
ding应助张潇潇采纳,获得10
17秒前
hh完成签到,获得积分10
18秒前
天真的南烟应助123采纳,获得10
18秒前
xujunjie发布了新的文献求助30
19秒前
20秒前
hanlululu完成签到 ,获得积分10
22秒前
23秒前
加油发布了新的文献求助10
24秒前
24秒前
27秒前
ntxiaohu完成签到,获得积分10
29秒前
张潇潇发布了新的文献求助10
29秒前
林楠完成签到,获得积分10
31秒前
半疯半癫发布了新的文献求助20
32秒前
32秒前
Tsing完成签到,获得积分10
32秒前
33秒前
高分求助中
LNG地下式貯槽指針(JGA指-107-19)(Recommended practice for LNG inground storage) 1000
rhetoric, logic and argumentation: a guide to student writers 1000
QMS18Ed2 | process management. 2nd ed 1000
Eric Dunning and the Sociology of Sport 850
Operative Techniques in Pediatric Orthopaedic Surgery 510
Generalized Linear Mixed Models 第二版 500
人工地层冻结稳态温度场边界分离方法及新解答 500
热门求助领域 (近24小时)
化学 医学 材料科学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 免疫学 细胞生物学 电极
热门帖子
关注 科研通微信公众号,转发送积分 2921018
求助须知:如何正确求助?哪些是违规求助? 2563349
关于积分的说明 6933820
捐赠科研通 2221229
什么是DOI,文献DOI怎么找? 1180754
版权声明 588757
科研通“疑难数据库(出版商)”最低求助积分说明 577670