ABSTRACTLong used in East Asian cuisine and traditional medicine, the brown seaweed Hizikia fusiformis (also known as Sargassum fusiforme or Hizikia fusiforme) is also referred to as “Hijiki.” Given its abundant environmental and bioactive characteristics, it has received considerable attention. This systematic review aimed to present comprehensive data from the existing literature on the environmental and bioactive characteristics of H. fusiformis. Using three databases to search for published studies on related fields between 2002 and 2023, 1344 papers were screened and narrowed down to a set of 49 papers by the predetermined criteria. Evidence shows that H. fusiformis is a promising resource in the environmental protection and bioactive domains. Overall, more research and methods are needed to organically combine the development of H. fusiformis in the environmental and bioactive fields to gain greater economic benefits and environmental protection capabilities.KEYWORDS: Hizikia fusiformeHizikia fusiformisSargassum fusiformeHijikibioactivityenvironmental Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThis work was supported by the [National Natural Science Foundation of China] under Grant [number 82204719]; [Jilin Scientific and Technological Development Program] under Grant [numbers YDZJ202201ZYTS004, 20210401065YY, and 20210204046YY]; and [Education Project of Jilin University] under Grant [numbers 419070600046, 45121031D024].