Screening of Associated Factors for Erectile Dysfunction after Radical Prostatectomy and Construction of a Clinical Risk Assessment Model: A Retrospective Study

医学 勃起功能障碍 前列腺切除术 逻辑回归 接收机工作特性 勃起功能 入射(几何) 优势比 回顾性队列研究 单变量分析 糖尿病 风险因素 多元分析 内科学 前列腺癌 泌尿科 癌症 物理 光学 内分泌学
作者
Zhibao Mi,Junyu Liu,L. Wang,Yuzhou Luo,Ke Yang
出处
期刊:Archivos españoles de urología [SciELO]
卷期号:77 (1): 92-92
标识
DOI:10.56434/j.arch.esp.urol.20247701.12
摘要

In this article, the associated factors for erectile dysfunction (ED) after radical prostatectomy (RP) were explored, and a clinical risk assessment model was constructed.A total of 155 patients who underwent RP in People's Hospital of Hunan Province from November 2020, to November 2021, were selected as the study group. In accordance with the results of International Index of Erectile Function (IIEF-5) at 6 months after surgery, 88 patients were included in the ED group (IIEF-5 <22), and 67 patients were included in the non-ED group (IIEF-5 ≥22). Univariate and multivariate logistic regression analyses were conducted to screen the risk factors for ED after RP, and a risk model was constructed on this basis. In addition, 43 patients with ED after RP and 41 patients with non-ED after RP from January 2022, to January 2023, were included in the test group to evaluate the predictive efficacy of the clinical risk assessment model on the basis of the receiver operating characteristic curve.The study group had a lower postoperative IIEF-5 score than before surgery (p < 0.001). The incidence of ED after RP in the study group was 56.77% (88/155). Multivariate analysis showed that advanced age (odds ratio (OR) = 1.155), large prostate volume (OR = 1.077), smoking (OR = 5.676), drinking (OR = 3.495), hypertension (OR = 8.079), diabetes (OR = 6.082), low preoperative serum testosterone (T) level (OR = 0.684) and high preoperative serum endothelin-1 (ET-1) level (OR = 1.192) were risk factors for ED after RP (p < 0.05). A risk model was constructed as follows: Z = 0.144 × (age) + 0.074 × (prostate volume) + 1.736 × (smoking) + 1.251 × (drinking) + 2.089 × (hypertension) + 1.805 × (diabetes) - 0.380 × (preoperative serum T) + 0.175 × (preoperative serum ET-1). The area under curve (AUC), sensitivity, specificity and 95% CI of this model were 0.906, 97.70%, 73.20%, and 0.848-0.964, respectively (p < 0.001).The clinical risk assessment model constructed on the basis of the above factors provides some references for the scientific prevention and treatment of ED after RP.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
善良的人发布了新的文献求助10
1秒前
怕黑的凝旋完成签到,获得积分10
1秒前
现代书雪完成签到,获得积分20
1秒前
彭于晏应助paltahun采纳,获得10
2秒前
斯文败类应助blawxx采纳,获得10
2秒前
bm发布了新的文献求助10
3秒前
3秒前
果冻橙发布了新的文献求助10
3秒前
xixi发布了新的文献求助10
3秒前
华仔应助Zenobia采纳,获得10
4秒前
5秒前
5秒前
学呀完成签到,获得积分10
5秒前
幸福胡萝卜完成签到,获得积分10
6秒前
健忘鞋垫完成签到,获得积分10
7秒前
AZURE完成签到,获得积分10
8秒前
lbj发布了新的文献求助10
8秒前
量子星尘发布了新的文献求助10
8秒前
白了个白发布了新的文献求助20
8秒前
完美世界应助嘟嘟采纳,获得10
9秒前
bobochi发布了新的文献求助30
9秒前
bm完成签到,获得积分10
10秒前
10秒前
羽羽完成签到 ,获得积分10
11秒前
xiaoxia完成签到,获得积分10
12秒前
14秒前
顾矜应助inferyes采纳,获得10
15秒前
oleskarabach发布了新的文献求助10
15秒前
听曲散步完成签到,获得积分10
16秒前
qq发布了新的文献求助10
17秒前
paltahun发布了新的文献求助10
17秒前
17秒前
科研民工李完成签到,获得积分10
17秒前
17秒前
娜娜完成签到 ,获得积分10
18秒前
L2发布了新的文献求助30
19秒前
花花猪1989发布了新的文献求助20
20秒前
李思发布了新的文献求助10
22秒前
liyq完成签到,获得积分10
23秒前
暮光微凉发布了新的文献求助10
23秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance 500
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3969940
求助须知:如何正确求助?哪些是违规求助? 3514642
关于积分的说明 11175298
捐赠科研通 3249947
什么是DOI,文献DOI怎么找? 1795178
邀请新用户注册赠送积分活动 875617
科研通“疑难数据库(出版商)”最低求助积分说明 804891