Screening of Associated Factors for Erectile Dysfunction after Radical Prostatectomy and Construction of a Clinical Risk Assessment Model: A Retrospective Study

医学 勃起功能障碍 前列腺切除术 逻辑回归 接收机工作特性 勃起功能 入射(几何) 优势比 回顾性队列研究 单变量分析 糖尿病 风险因素 多元分析 内科学 前列腺癌 泌尿科 癌症 物理 光学 内分泌学
作者
Zhibao Mi,Junyu Liu,L. Wang,Yuzhou Luo,Ke Yang
出处
期刊:Archivos españoles de urología [SciELO]
卷期号:77 (1): 92-92
标识
DOI:10.56434/j.arch.esp.urol.20247701.12
摘要

In this article, the associated factors for erectile dysfunction (ED) after radical prostatectomy (RP) were explored, and a clinical risk assessment model was constructed.A total of 155 patients who underwent RP in People's Hospital of Hunan Province from November 2020, to November 2021, were selected as the study group. In accordance with the results of International Index of Erectile Function (IIEF-5) at 6 months after surgery, 88 patients were included in the ED group (IIEF-5 <22), and 67 patients were included in the non-ED group (IIEF-5 ≥22). Univariate and multivariate logistic regression analyses were conducted to screen the risk factors for ED after RP, and a risk model was constructed on this basis. In addition, 43 patients with ED after RP and 41 patients with non-ED after RP from January 2022, to January 2023, were included in the test group to evaluate the predictive efficacy of the clinical risk assessment model on the basis of the receiver operating characteristic curve.The study group had a lower postoperative IIEF-5 score than before surgery (p < 0.001). The incidence of ED after RP in the study group was 56.77% (88/155). Multivariate analysis showed that advanced age (odds ratio (OR) = 1.155), large prostate volume (OR = 1.077), smoking (OR = 5.676), drinking (OR = 3.495), hypertension (OR = 8.079), diabetes (OR = 6.082), low preoperative serum testosterone (T) level (OR = 0.684) and high preoperative serum endothelin-1 (ET-1) level (OR = 1.192) were risk factors for ED after RP (p < 0.05). A risk model was constructed as follows: Z = 0.144 × (age) + 0.074 × (prostate volume) + 1.736 × (smoking) + 1.251 × (drinking) + 2.089 × (hypertension) + 1.805 × (diabetes) - 0.380 × (preoperative serum T) + 0.175 × (preoperative serum ET-1). The area under curve (AUC), sensitivity, specificity and 95% CI of this model were 0.906, 97.70%, 73.20%, and 0.848-0.964, respectively (p < 0.001).The clinical risk assessment model constructed on the basis of the above factors provides some references for the scientific prevention and treatment of ED after RP.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
Cu_wx完成签到,获得积分10
1秒前
噜噜噜噜噜完成签到,获得积分10
3秒前
赵慧霞关注了科研通微信公众号
3秒前
炎魔之王拉格纳罗斯完成签到,获得积分10
4秒前
内向苡完成签到,获得积分10
5秒前
以筱发布了新的文献求助10
7秒前
bhkwxdxy完成签到,获得积分10
8秒前
悦耳虔纹完成签到 ,获得积分10
8秒前
xx完成签到,获得积分10
8秒前
大气灵枫完成签到,获得积分10
8秒前
妮妮完成签到,获得积分10
9秒前
11秒前
Struggle完成签到 ,获得积分10
12秒前
12秒前
秦兴虎完成签到,获得积分10
13秒前
Drew11完成签到,获得积分10
13秒前
风趣青槐完成签到,获得积分10
15秒前
科隆龙完成签到,获得积分10
16秒前
16秒前
饱满一手完成签到 ,获得积分10
16秒前
99完成签到,获得积分10
18秒前
枕星发布了新的文献求助10
18秒前
drlq2022完成签到,获得积分10
19秒前
王山完成签到,获得积分10
20秒前
自觉寒梦完成签到,获得积分10
21秒前
ding应助缥缈一刀采纳,获得10
21秒前
pakiorder发布了新的文献求助10
21秒前
专心搞学术完成签到,获得积分10
21秒前
bkagyin应助zzcherished采纳,获得10
23秒前
你怎么这么可爱啊完成签到,获得积分10
23秒前
24秒前
研友_Lmg1gZ完成签到,获得积分10
24秒前
Crazyer完成签到,获得积分10
24秒前
Shuey完成签到,获得积分10
25秒前
XXXXH完成签到,获得积分10
25秒前
Z可完成签到 ,获得积分10
26秒前
momo123完成签到 ,获得积分10
26秒前
高兴的书竹完成签到 ,获得积分10
27秒前
mp5完成签到,获得积分10
28秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038303
求助须知:如何正确求助?哪些是违规求助? 3576013
关于积分的说明 11374210
捐赠科研通 3305780
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029