Lifestyle predictors of obese and non-obese patients with nonalcoholic fatty liver disease: A cross-sectional study

医学 非酒精性脂肪肝 内科学 肥胖 胰岛素抵抗 脂肪组织 内分泌学 脂肪肝 体质指数 人体测量学 甘油三酯 腹部肥胖 生理学 代谢综合征 胃肠病学 疾病 胆固醇
作者
Joo Hee Kwak,Dae Won Jun,Seung Min Lee,Yong Kyun Cho,Kang Nyeong Lee,Hang Lak Lee,Oh Young Lee,Ho Soon Choi,Byung Chul Yoon
出处
期刊:Clinical Nutrition [Elsevier]
卷期号:37 (5): 1550-1557 被引量:19
标识
DOI:10.1016/j.clnu.2017.08.018
摘要

Most people with nonalcoholic fatty liver disease (NAFLD) are obese, and they usually eat more while being less physically active as compared to healthy individuals. However, little is known about the lifestyle patterns of non-obese or obese patients with NAFLD. The aim of this study was to investigate nutrition components and behavioral differences between non-obese and obese patients with NAFLD.This is a cross-sectional study comprising of 209 patients. Nutritional components and physical activity status were compared in obese and non-obese subjects with NAFLD against healthy controls. Dietary intake was assessed using the 5-day food diary. Physical activity was measured using the protocol of Korea Health and Nutrition Examination Survey. Total and regional body composition analysis was conducted using anthropometry and tetrapolar multi-frequency bio-impedance. Visceral adipose tissue, total abdominal adipose tissue, abdominal subcutaneous adipose tissue as well as liver fat were measured using abdomen tomography.Non-obese subjects with NAFLD had higher levels of ALT, AST, GGT, triglyceride, fasting glucose; higher carbohydrate energy ratio; higher visceral fat area, subcutaneous area, body muscle mass, fat free mass and body fat compared to subjects without NAFLD. Subjects with obesity and NAFLD had higher ALT, AST, visceral fat, fasting glucose and HOMA-IR (homeostatic model assessment-insulin resistance), and less moderate-level physical activity compared to those with obesity who do not have NAFLD. Obese subjects with NAFLD also had higher blood pressure, visceral fat area, subcutaneous fat area, body fat, body fat percent and GGT compared to non-obese subjects with NAFLD. In multivariate analysis, carbohydrate energy ratio and physical activity less than moderate-level (<2 h/week) were predictors of NAFLD in non-obese subjects independent of the visceral fat, body muscle index, total energy intake, age and sex. Physical activity less than moderate-level was a predictor of NAFLD in obese subjects with NAFLD, independent of the HOMA-IR, visceral fat, total energy intake, fat energy percent, age and sex.Percentage of carbohydrate intake percent and physical activity, less than moderate-level were independent predictors of NAFLD in non-obese subjects. Meanwhile, physical activity, less than moderate-level, was an independent predictor in obese subjects.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
研友_8yVV0L完成签到 ,获得积分10
刚刚
刚刚
3秒前
4秒前
lucky完成签到 ,获得积分10
4秒前
4秒前
淡然发布了新的文献求助10
6秒前
科目三应助yixia222采纳,获得10
6秒前
清爽代双完成签到,获得积分10
7秒前
8秒前
9秒前
Smry完成签到,获得积分10
9秒前
野性的曼香完成签到,获得积分10
10秒前
11秒前
11秒前
共享精神应助lanxinge采纳,获得10
12秒前
Maestro_S发布了新的文献求助30
13秒前
满意发布了新的文献求助10
13秒前
上官若男应助zxy采纳,获得10
14秒前
wxc完成签到,获得积分10
14秒前
赘婿应助尔尔采纳,获得10
14秒前
x123完成签到,获得积分10
15秒前
小蘑菇应助更远的天空采纳,获得10
15秒前
文森特的向日葵完成签到,获得积分10
15秒前
17秒前
WeiBao发布了新的文献求助10
17秒前
19秒前
淡然完成签到,获得积分10
20秒前
shuke完成签到,获得积分10
21秒前
Ainra完成签到,获得积分10
22秒前
22秒前
丘比特应助晚风中追风采纳,获得10
22秒前
结实灭男发布了新的文献求助10
23秒前
Lucie完成签到,获得积分20
23秒前
sgaaufe发布了新的文献求助10
27秒前
zxy发布了新的文献求助10
27秒前
28秒前
WeiBao完成签到,获得积分10
28秒前
守护星星完成签到,获得积分10
29秒前
高分求助中
Evolution 10000
Sustainability in Tides Chemistry 2800
юрские динозавры восточного забайкалья 800
English Wealden Fossils 700
An Introduction to Geographical and Urban Economics: A Spiky World Book by Charles van Marrewijk, Harry Garretsen, and Steven Brakman 500
Diagnostic immunohistochemistry : theranostic and genomic applications 6th Edition 500
Chen Hansheng: China’s Last Romantic Revolutionary 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3151673
求助须知:如何正确求助?哪些是违规求助? 2803099
关于积分的说明 7851899
捐赠科研通 2460474
什么是DOI,文献DOI怎么找? 1309813
科研通“疑难数据库(出版商)”最低求助积分说明 629061
版权声明 601760