生物
猪繁殖与呼吸综合征病毒
病毒学
爆发
病毒
免疫系统
病菌
免疫学
作者
Taofeng Du,Yuchen Nan,Shuqi Xiao,Qin Zhao,En‐Min Zhou
标识
DOI:10.1016/j.tim.2017.06.001
摘要
PRRSV (porcine reproductive and respiratory syndrome virus) is a major economically significant pathogen that has adversely impacted the global swine industry for almost 30 years. Currently PRRSV is estimated to cause losses of almost US$600 million per year in the USA. Except for new mutants that continually emerge during PRRSV outbreaks, our understanding of the virology, origin, and evolution of PRRSV and the host's immune response are largely inadequate. Such limited knowledge impedes development of effective methods to eradicate this virus. In this review, we systematically describe recent advances in anti-PRRSV research, especially focusing on those techniques with the potential to transform current anti-PRRSV strategies. Furthermore, a combination of these new techniques may provide creative insights to guide future PRRSV control and prevention.
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