化学
合成子
试剂
催化作用
酰化
组合化学
碳酸盐
荧光
功能群
铑
有机化学
聚合物
物理
量子力学
作者
Wei Hu,Chao Pi,Di Hu,Xiliang Han,Yangjie Wu,Xiuling Cui
出处
期刊:Organic Letters
[American Chemical Society]
日期:2022-04-04
卷期号:24 (14): 2613-2618
被引量:23
标识
DOI:10.1021/acs.orglett.2c00580
摘要
A rhodium-catalyzed cyclization of azobenzenes and vinylene carbonate via C-H bond activation to construct indazolo[2,3-a]quinolines has been developed. This protocol offers an efficient method for synthesis of the titled products in good yields with broad functional group tolerance. In this reaction, three C-C bonds and C-N bond are formed in one pot, and vinylene carbonate (VC) acts as C1 and C2 synthons as well as "vinylene transfer" agent and acylation reagent in the construction of target-fused heterocycles. Moreover, the products exhibit favorable fluorescence properties, which indicate their potential application as fluorescent materials and biosensors.
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