Advance About Molecular Genetics of Melatonin Receptor 1A Gene(MTNR1A)

Melatonin(MEL) is an endocrine hormone secreted by the pineal gland and retina, which has a wide range of biological functions through binding with melatonin receptor(MTNR). This review introduced the structure, expression, cloning,mapping, polymorphism and trait association analysis of melatonin receptor1A gene(MTNR1A) in different species, proposed the research emphasis of MTNR1A gene in the future, and focused on the relationship between MTNR1A and reproductive seasonality. This article may provide theoretical references for reproductive seasonality mechanism research.