白血病
谱系(遗传)
染色体易位
基因
等位基因
医学
遗传学
癌症研究
生物
作者
Jolanta Grembecka,Tomasz Cierpicki
标识
DOI:10.1056/nejmcibr1700964
摘要
The translocation of the gene encoding mixed lineage leukemia with other genes results in chimeric, oncogenic proteins. A recent study shows that stabilization of wild-type MLL (encoded by the untranslocated allele) is an experimental approach to treating leukemia.
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