Ultrasound Shear Wave Elastography: A Novel Method to Evaluate Bladder Pressure

No AccessJournal of UrologyPediatric Urology1 Aug 2017Ultrasound Shear Wave Elastography: A Novel Method to Evaluate Bladder Pressure Renea M. Sturm, Elizabeth B. Yerkes, Jennifer L. Nicholas, Devon Snow-Lisy, Dawn Diaz Saldano, P. Lacy Gandor, Christopher G. Halline, Ilina Rosoklija, Karen Rychlik, Emilie K. Johnson, and Earl Y. Cheng Renea M. SturmRenea M. Sturm Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , Elizabeth B. YerkesElizabeth B. Yerkes Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , Jennifer L. NicholasJennifer L. Nicholas Department of Radiology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , Devon Snow-LisyDevon Snow-Lisy Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , Dawn Diaz SaldanoDawn Diaz Saldano Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , P. Lacy GandorP. Lacy Gandor Department of Radiology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , Christopher G. HallineChristopher G. Halline Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , Ilina RosoklijaIlina Rosoklija Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , Karen RychlikKaren Rychlik Biostatistics Research Core, Stanley Manne Research Institute, Chicago, Illinois More articles by this author , Emilie K. JohnsonEmilie K. Johnson Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author , and Earl Y. ChengEarl Y. Cheng Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.03.127AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Children with bladder dysfunction resulting in increased storage pressure are at risk for renal deterioration. The current gold standard for evaluation of bladder pressure is urodynamics, an invasive test requiring catheterization. We evaluated ultrasound shear wave elastography as a novel means of assessing bladder biomechanical properties associated with increased bladder pressure. Materials and Methods: Concurrent shear wave elastography and urodynamics were performed. Ultrasound shear wave elastography images were obtained of the anterior and posterior wall when empty and at 25%, 50%, 75% and 100% expected bladder capacity, and end fill volume. Regions of interest were confirmed by a pediatric radiologist. Bladder cohorts were defined as compliant (capacity detrusor pressure less than 25 cm H2O) and noncompliant (25 cm H2O or greater). Pearson correlation coefficients and a mixed effects model evaluated the relationship between shear wave speed and detrusor pressure, compliance and normalized compliance. An unpaired t-test was used for between cohort analyses. Results: In all 23 subjects mean shear wave speed of the anterior and posterior bladder walls significantly correlated with detrusor pressure throughout filling. When comparing compliant and noncompliant bladders, mean shear wave speed and detrusor shear wave speed of the anterior wall significantly increased with filling of noncompliant bladders. Shear wave speed remained at baseline levels in compliant bladders. Mean shear wave speed of the anterior wall was significantly correlated with compliance and normalized compliance. 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Google Scholar 26 Shepard CL, Smith EA, Dillman JR et al: Acoustic radiation force imaging (ARFI) does not predict abnormal urodynamic parameters in children. Presented at Pediatric Urology Fall Congress, Dallas, Texas, September 9-11, 2016. Google Scholar © 2017 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byCain M (2017) This Month in Pediatric UrologyJournal of Urology, VOL. 198, NO. 2, (223-223), Online publication date: 1-Aug-2017. Volume 198Issue 2August 2017Page: 422-429Supplementary Materials Advertisement Copyright & Permissions© 2017 by American Urological Association Education and Research, Inc.Keywordsurodynamicsneurogenicelasticity imaging techniquesfibrosisurinary bladderurinary bladderMetricsAuthor Information Renea M. Sturm Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Elizabeth B. Yerkes Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Jennifer L. Nicholas Department of Radiology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Devon Snow-Lisy Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Dawn Diaz Saldano Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author P. Lacy Gandor Department of Radiology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Christopher G. Halline Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Ilina Rosoklija Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Karen Rychlik Biostatistics Research Core, Stanley Manne Research Institute, Chicago, Illinois More articles by this author Emilie K. Johnson Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Earl Y. Cheng Division of Urology, Ann and Robert H. Lurie Children’s Hospital, Chicago, Illinois More articles by this author Expand All Advertisement PDF downloadLoading ...