The role of tender and swollen joints for the assessment of inflammation in PsA using ultrasound

医学 滑膜炎 温柔 优势比 超声波 内科学 体格检查 外科 关节炎 放射科
作者
Philipp Bösch,Angelika Lackner,Barbara Dreo,Rusmir Husic,Anja Ficjan,Judith Gretler,W. Graninger,Christina Duftner,Josef Hermann,Christian Dejaco
出处
期刊:Rheumatology [Oxford University Press]
卷期号:61 (SI): SI92-SI96 被引量:4
标识
DOI:10.1093/rheumatology/keab764
摘要

To evaluate tender joints (TJ) and swollen joints (SJ) for the assessment of ultrasound (US) defined inflammation in PsA.Eighty-three PsA patients underwent clinical and US examinations at two scheduled study visits 12 months apart. Tenderness and swelling were assessed at 68 and 66 joints, respectively, and US examinations were conducted at all 68 joints. At patient level, associations with clinical composites and US scores were performed using correlations and by analysing patients with predominantly tender (pTender) or swollen joints (pSwollen). At joint level, a Power Doppler (PD) value ≥ 1 was defined as active synovitis. A generalized linear mixed model was created to assess the predictive value of TJ and SJ for active synovitis after 12 months.SJC showed better correlations with GS/PD scores (r = 0.37/0.47) than with TJC (PD: r = 0.33), while TJC correlated better with patient reported outcomes (PROMs) like patient global assessment (TJC: r = 0.57; SJC r = 0.39). Patients with pTender showed poorer results for PROMs and disease activity scores than patients with pSwollen, but not for laboratory or US markers of inflammation. Swollen joints showed active synovitis in 35% of cases, while only 16% of tender joints were active according to US. Swelling at baseline better predicted active synovitis at the same joint after 12 months [odds ratio (OR) 6.33, P <0.001] as compared with tenderness (OR 3.58, P <0.001).SJ are more closely linked with US signs of inflammation as compared with TJ in PsA. Joint swelling is a better predictor for signs of US inflammation than tenderness after one year of follow-up.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
何三岁完成签到,获得积分10
刚刚
浪里白条完成签到,获得积分10
1秒前
1秒前
2秒前
苦雨完成签到,获得积分10
4秒前
LINHAI发布了新的文献求助10
5秒前
研友_Z63Wg8完成签到,获得积分10
5秒前
6秒前
7秒前
7秒前
不配.应助礼拜天采纳,获得10
8秒前
8秒前
Yuheart发布了新的文献求助10
8秒前
高产佩奇完成签到,获得积分10
10秒前
11秒前
11秒前
鲤鱼问雁完成签到,获得积分10
12秒前
wildtypeho发布了新的文献求助10
14秒前
16秒前
16秒前
伊小美发布了新的文献求助10
17秒前
moon发布了新的文献求助10
17秒前
18秒前
充电宝应助Yuheart采纳,获得10
18秒前
喝奶茶睡不着完成签到,获得积分10
18秒前
隐形白开水完成签到,获得积分10
19秒前
灵寒完成签到 ,获得积分10
19秒前
20秒前
燕子完成签到 ,获得积分10
20秒前
Moonlight完成签到 ,获得积分10
20秒前
wildtypeho完成签到,获得积分10
20秒前
diyacao发布了新的文献求助10
21秒前
小焦儿发布了新的文献求助10
22秒前
22秒前
小狗发布了新的文献求助10
24秒前
喜悦香薇发布了新的文献求助10
25秒前
25秒前
Hyacinth发布了新的文献求助10
26秒前
波粒海苔完成签到,获得积分20
27秒前
28秒前
高分求助中
Sustainability in Tides Chemistry 2800
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
Rechtsphilosophie 1000
Bayesian Models of Cognition:Reverse Engineering the Mind 888
Le dégorgement réflexe des Acridiens 800
Defense against predation 800
Very-high-order BVD Schemes Using β-variable THINC Method 568
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3135127
求助须知:如何正确求助?哪些是违规求助? 2786103
关于积分的说明 7775305
捐赠科研通 2441924
什么是DOI,文献DOI怎么找? 1298299
科研通“疑难数据库(出版商)”最低求助积分说明 625112
版权声明 600839