微泡
外体
计算生物学
诊断生物标志物
癌症
蛋白质组学
癌症研究
小RNA
癌症生物标志物
生物标志物
生物信息学
医学
生物
基因
遗传学
内科学
作者
Ruhua Luo,Mengmeng Liu,Qian Yang,Han Cheng,Huimin Yang,Min-Hui Li,Xue Bai,Yue Wang,Honghua Zhang,Shuling Wang,Tian Xie,Qingchang Tian
出处
期刊:Journal of Cancer
[Ivyspring International Publisher]
日期:2021-01-01
卷期号:12 (16): 5035-5045
被引量:13
摘要
Exosomes carry genetic information originating from their parental cells, raising their possibility as novel noninvasive biomarkers for cancer.Tumor-derived exosomes (TEXs) have a variety of endogenous cargos that reflect the pathophysiology status and information of tumor cells.TEXs are increasingly being recognized as potential biomarkers for cancer diagnosis prognosis, and monitoring.It is important to develop a variety of sensitive methods, including probes and biomaterials to isolate exosomes.A variety of approaches for detecting exosomes have been established.By combining exosome DNA and RNA sequencing tools, exosome proteomics analysis and immunoassay technology, it is expected that exosomes will gain widespread use in the diagnosis and treatment of cancer.
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