富维斯特朗
帕博西利布
医学
危险系数
内科学
肿瘤科
安慰剂
乳腺癌
转移性乳腺癌
芳香化酶抑制剂
癌症
妇科
置信区间
雌激素受体
三苯氧胺
病理
替代医学
作者
Nicholas C. Turner,Dennis J. Slamon,Jungsil Ro,Igor Bondarenko,Seock‐Ah Im,Norikazu Masuda,Marco Colleoni,Angela DeMichele,Sherene Loi,Sunil Verma,Hiroji Iwata,Nadia Harbeck,Sibylle Loibl,Fabrice André,Kathy Puyana Theall,Xin Huang,C. Giorgetti,Cynthia Huang Bartlett,Massimo Cristofanilli
标识
DOI：10.1056/nejmoa1810527
摘要
The cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor palbociclib, in combination with fulvestrant therapy, prolongs progression-free survival among patients with hormone-receptor–positive, human epidermal growth factor receptor 2 (HER2)–negative advanced breast cancer. We report the results of a prespecified analysis of overall survival.
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