Electrochemical sensing of anti-inflammatory agent in paramedical sample based on FeMoSe2 modified SPCE: Comparison of various preparation methods and morphological effects

We demonstrate the different types of synthesis processes (hydrothermal, microwave and simple chemical synthesis) to prepare the Fe doped molybdenum diselenides (H-FeMoSe2, M-FeMoSe2, and C-FeMoSe2) and investigate their relevant electrocatalytic activities. The Fe doped MoSe2 exhibited an enhanced charge transfer conductivity and electrocatalytic activity. Especially, the H-FeMoSe2 with vertically aligned structures facilitate the abundant exposed active edge sites. Thus, H-FeMoSe2 modified screen-printed carbon electrode (H-FeMoSe2/SPCE) exhibited the lower Rct and better active surface area than that of M-FeMoSe2/SPCE and C-FeMoSe2/SPCE. As well as, the electrochemical sensing of mesalamine (MES) at H-FeMoSe2/SPCE is comparatively 0.46 and 1.28 fold higher than that obtained at M-FeMoSe2/SPCE and C-FeMoSe2/SPCE respectively. Thus, H-FeMoSe2/SPCE was concluded as an excellent electrocatalyst for sensing of MES and performed DPV technique. As the results, very low detection limit (0.8 nM) of MES was achieved at H-FeMoSe2/SPCE. Hence, the selected H-FeMoSe2/SPCE was successfully subjected to the real-time detection of MES by using a paramedical tablet and reported the excellent recovery range.