Enzymatic radiosynthesis of a18F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)

FDA-PEG-GUL was enzymatically synthesised using the fluorinase in¹⁸F-radiolabelled form and shown to efficiently bind the prostate-specific antigen (PSMA) which is upregulated in prostate cancer cells.