化学
芳构化
卤化
组合化学
有机化学
药物化学
催化作用
作者
Mi Lian,Qi Li,Yan‐Ping Zhu,Guodong Yin,An‐Xin Wu
出处
期刊:Tetrahedron
[Elsevier]
日期:2012-11-01
卷期号:68 (47): 9598-9605
被引量:65
标识
DOI:10.1016/j.tet.2012.09.056
摘要
A novel protocol for the synthesis of quinoxalines has been developed from simple ketones and 1,2-diamines. This process underwent a logic approach to bis-substituted quinoxalines via a consecutive iodination/Kornblum oxidation/cyclization in the presence of I2/CuO/DMSO and to mono-substituted quinoxalines via an iodination/cyclization/aromatization in the presence of I2/CuO/K3PO4·3H2O.
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