Synthesis of a new enantiopure chiral aza crown ether and its application in enantiomeric separation

A new enantiopure chiral aza crown ether (S,S)-1,7-bis(4-phenyl-5-hydroxy-2-oxo-3- zapentyl)-1,7-diaza-12-crown-4 ligand (1) has been synthesized and used as a chiral selector in the enantiomeric separation of D/L-carnitine by capillary electrophoresis.