牛磺酸
卵母细胞
人类受精
毛囊
内科学
内分泌学
体外受精
劈理(地质)
生物
刺激
激素
化学
男科
细胞生物学
胚胎
解剖
生物化学
医学
古生物学
氨基酸
断裂(地质)
作者
Teng Mu,Ying Feng,Yuchen Che,Qiufeng Lv,Jianmin Hu,Qunhui Yang,Jiancheng Yang
标识
DOI:10.1007/978-981-13-8023-5_18
摘要
It is well known that a large quantity of taurine is present in mammalian ovaries. Taurine reportedly promotes the secretion of female reproductive hormones by stimulating hypothalamus-pituitary-gonadal axis function. Therefore, we speculated that taurine may have beneficial effects on follicle growth, oocyte maturation, fertilization and cleavage. Here, we cultured rat follicles, immature oocytes and sperms in vitro and treated with taurine to observe the changes in follicle diameter, estradiol concentration as well as the rate of oocytes maturation, fertilization and cleavage using an inverted microscope. The results showed that taurine can elevate ovarian follicles growth and oocyte maturation, fertilization, and cleavage rates in vitro, which may be attributed to its osmoregulation and stimulation on the estradiol secretion. Our results provide important insights into taurine application in female production, although the underlying mechanism need to be further addressed.
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