样本量测定
经验法则
背景(考古学)
统计
协议(科学)
数学
差异(会计)
计算机科学
样品(材料)
心理学
医学
地理
替代医学
经济
病理
考古
化学
会计
色谱法
算法
摘要
Abstract When designing a clinical trial an appropriate justification for the sample size should be provided in the protocol. However, there are a number of settings when undertaking a pilot trial when there is no prior information to base a sample size on. For such pilot studies the recommendation is a sample size of 12 per group. The justifications for this sample size are based on rationale about feasibility; precision about the mean and variance; and regulatory considerations. The context of the justifications are that future studies will use the information from the pilot in their design. Copyright © 2005 John Wiley & Sons, Ltd.
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