内分泌学
内科学
间歇性禁食
生物
肥胖
热量理论
医学
作者
Everton Luis dos Santos Cardoso,Fábio Cahuê,Iordan Emanuel Ferreira Miranda,Marcelo de Lima Sant’Anna,Cherley Borba Vieira de Andrade,Raiana Andrade Quintanilha Barbosa,Tania Maria Ortiga‐Carvalho,Mário Vaisman,Verônica P. Salerno
出处
期刊:Tissue & Cell
[Elsevier]
日期:2023-06-01
卷期号:82: 102099-102099
被引量:1
标识
DOI:10.1016/j.tice.2023.102099
摘要
High caloric intake and physical inactivity are known precursors to the development of several chronic metabolic diseases. For obesity and sedentarism, High Intensity Intermittent Exercise (HIIE) and Intermittent Fasting (IF) have emerged as individual strategies to attenuate their negative effects by improving metabolism. To study their combined effects, Wistar male rats (n = 74, 60 days old) were divided into four groups: Sedentary Control (C), swimming-based HIIE only (HIIE), Intermittent Fasting only (IF), and swimming-based HIIE associated with Intermittent Fasting (HIIE/IF). Over an eight-week period swimming performance, body composition, weight and feeding behavior were analyzed. The final morphology of white adipose tissue showed a significant reduction in adipocyte size consistent with a higher number of cells per area in exercised animals (vs C and IF, p < 0.05), which also displayed characteristics of browning through UCP-1 levels and CD31 staining. These results suggest that the increased performance in the HIIE/IF group is, in part, by modifications of WAT metabolism through the browning process.
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