Lewis Acid‐catalyzed Tandem Synthesis of Quinazoline‐2,4‐diones by Reaction of Isatins with Aryl/Alkyl Amines using TBHP as Oxidant

Abstract A new and efficient method for preparation of quinazoline‐2,4‐diones by tandem reaction of isatins with aryl/alkyl amines via oxidative rearrangement in the presence of Lewis acid/TBHP is described. This method offers a new approach with wide substrate scope for preparation of quinazoline‐2,4‐diones, in highyields under mild conditions.