Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal (Monteiro A, Monteiro S, Silva NA) ICVS/3B's Associate Lab, PT Government Associated Lab, Braga/Guimarães, Portugal (Monteiro A, Monteiro S, Silva NA) *Correspondence to: Nuno A. Silva, PhD, [email protected]. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.