表观遗传学
调节器
染色质
染色质重塑
背景(考古学)
生物
后生
疾病
生物信息学
遗传学
医学
DNA甲基化
基因表达
基因
内科学
古生物学
作者
Zi-Yue Ma,Jing Li,Xian-Hui Dong,Ying-Tao Cui,Yunfeng Cui,Tao Ban,Rong Huo
标识
DOI:10.1016/j.ejphar.2023.176039
摘要
Cardiovascular diseases have been closely linked to abnormal epigenetic regulation. In the context of epigenetic regulation, BRG1, a pivotal SWI/SNF chromatin remodeling enzyme, emerges as a key epigenetic regulator with significant impact on the development and progression of cardiovascular disorders. From the perspective of epigenetic regulation of cardiovascular diseases, BRG1 emerges as a pivotal SWI/SNF chromatin remodeling enzyme, functioning as a key epigenetic regulator. It exerts substantial influence on the development and progression of cardiovascular disorders by exerting precise control over gene expression and protein levels. Therefore, a comprehensive understanding of BRG1's epigenetic regulatory role in cardiovascular disease is essential for unraveling its underlying pathophysiological mechanisms. This paper summarizes and discusses the function of BRG1 in the epigenetic regulation of cardiovascular diseases.
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