医学
鼻息肉
息肉切除术
嗅觉系统
嗅觉标记蛋白
嗅粘膜
病理
解剖
嗅上皮
内科学
癌症
结肠镜检查
结直肠癌
精神科
作者
Mahmood F. Bhutta,S Al-Shaikh,Mazlyzam Abdul Latif,R Lee,J Uraiby
出处
期刊:Rhinology
[Rhinology]
日期:2011-06-01
卷期号:49 (2): 185-189
被引量:8
摘要
BACKGROUND: Nasal polyposis can lead to olfactory dysfunction, either due to physical obstruction of the olfactory cleft or physiological disruption of the olfactory neuroepithelium. Where medical therapy has failed to relieve symptoms of nasal polyposis, surgical excision can be considered. However, removal of polyps medial to the middle turbinate is controversial: some believe this will relieve physical obstruction to odourants, others state that removal here risks excising olfactory neuroepithelium. METHODS: We stained 25 nasal polypectomy samples from the area medial to the middle turbinate with olfactory marker protein. RESULTS: We confirmed that our staining method worked on normal olfactory tissue. However, no positive staining of nasal polyps was demonstrated. CONCLUSION: We conclude that nasal polyps medial to the middle turbinate do not contain olfactory neurons, and surgical excision is not contraindicated.
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