间充质干细胞
卵巢癌
干细胞
叙述性评论
放射治疗
医学
骨髓
脐带
癌症研究
肿瘤科
癌症
生物信息学
生物
病理
内科学
免疫学
细胞生物学
重症监护医学
作者
Saleheh Jahani,Nabi Zare,Yousef Mirzaei,Reza Arefnezhad,Hooman Zarei,Pouya Goleij,Nader Bagheri
摘要
Ovarian cancer (OC) is described as a heterogeneous complex condition with high mortality, weak prognosis, and late-stage presentation. OC has several subgroups based on different indices, like the origin and histopathology. The current treatments against OC include surgery followed by chemotherapy and radiotherapy; however, these methods have represented diverse side effects without enough effectiveness on OC. Recently, mesenchymal stem cell (MSC)-based therapy has acquired particular attention for treating diverse problems, such as cancer. These multipotent stem cells can be obtained from different sources, such as the umbilical cord, adipose tissues, bone marrow, and placenta, and their efficacy has been investigated against OC. Hence, in this narrative review, we aimed to review and discuss the present studies about the effects of various sources of MSCs on OC with a special focus on involved mechanisms.
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