鲍曼不动杆菌
爆发
打字
微生物学
重症监护室
脉冲场凝胶电泳
重症监护
医学
生物
铜绿假单胞菌
重症监护医学
病毒学
细菌
基因型
遗传学
基因
作者
Donatella Lombardo,Miriam Cordovana,Francesca Deidda,Marco Pane,Simone Ambretti
标识
DOI:10.2217/fmb-2020-0276
摘要
Aim:Acinetobacter baumannii is a pathogen of serious concern, often exhibiting multiple antibiotic resistance, frequently associated with hospital outbreaks in intensive care units. A prompt detection and tracking of these isolates is crucial. Reference methods for typing (pulsed-field gel electrophoresis, whole-genome sequencing) are accurate, but expensive and time-consuming, therefore limited to retrospective analysis. Materials & methods: In this study, the application of the FTIR-based IR Biotyper® (IRBT) to track and monitor in real-time the spread of a multidrug-resistant A. baumannii outbreak was investigated. The index case and the multidrug-resistant A. baumannii isolates collected in the following 3 weeks were investigated. Results: IR Biotyper® clustering results were fully confirmed by pulsed-field gel electrophoresis results. Conclusions: IR Biotyper represent a promising tool for real-time hospital hygiene, enabling a prompt and reliable typing.
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