Na2 Eosin Y Catalyzed Alkylation of Enol Acetates by Radical Decarboxylation of N‐Hydroxyphthalimide Esters

Abstract A novel, efficient and transition‐metal‐free alkylation of enol acetates by radical decarboxylation of N‐hydroxyphthalimide esters to synthesize α‐alkylated ketones in existence of Na 2 ‐eosin Y at room temperature has been developed. This methodology features operational simplicity, mild reaction conditions, widely functional group tolerance, affording a diverse array of α‐alkylated ketones in moderate to good yields.