Study on the relationship between obesity and gastroesophageal reflux disease

Objective To investigate the relationship between obesity and esophageal high resolutionmanometry, 24-hour pH monitoring and gastroscopic results of patients with gastroesophageal reflux disease (GERD). Methods A total of 196 patients with GERD(DeMeester score>14.72) were selected and divided into normal weight group (18.5 kg/m20.05). Conclusions Compared with that of normal weight group and overweight group of patiento with GERD, abdominal length of LES of obesity group was shorter. With an increase in BMI, acid exposure and the incidences of reflux esophagitis and hiatal hernia also increased. Key words: Gastroesophageal reflux; Esophageal high resolution manometry; BMI; Esophageal pH monitoring; Obesity