神经病理性疼痛
自噬
医学
液泡
神经科学
药理学
作者
Yuhong Sun,Rui Li,Ye Zhang
出处
期刊:International Journal of Anesthesiology and Resuscitation
[Chinese Medical Association]
日期:2018-02-15
卷期号:39 (2): 161-164
标识
DOI:10.3760/cma.j.issn.1673-4378.2018.02.016
摘要
Background
Autophagy is a degradative process that cells dispose of cytosolic proteins and organelles, then enter into vacuole, fuse with lysosomes and form autolysosomes for degradation. Neuropathic pain is a direct consequence of an injury or disease affecting the somatosensory system, which can be caused by injury or disease to peripheral or central nervous system. It plays an important role in neuropathic pain.
Objective
The role of autophagy in neuropathic pain was reviewed.
Content
The effects of activation or inhibition of autophagy on neuropathic pain, the mechanisms of autophagy mediated neuropathic pain and the effects of neuropathic pain on autophagy.
Trend
Autophagy may provide theoretical foundation for the treatment of neuropathic pain.
Key words:
Autophagy; Neuropathic pain
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