Manganese complexes and manganese-based metal-organic frameworks as contrast agents in MRI and chemotherapeutics agents: Applications and prospects

生物相容性 金属有机骨架 合理设计 纳米技术 材料科学 组合化学 磁共振造影剂 化学 纳米颗粒 有机化学 吸附
作者
Rouqiao Zheng,Jun-Ru Guo,Xinyi Cai,Lianjie Bin,Chengyu Lu,Amita Singh,Manoj Trivedi,Abhinav Kumar,Jian-Qiang Liu
出处
期刊:Colloids and Surfaces B: Biointerfaces [Elsevier]
卷期号:213: 112432-112432 被引量:75
标识
DOI:10.1016/j.colsurfb.2022.112432
摘要

Manganese-based Metal-organic Frameworks (Mn-MOFs) represents a unique sub-class of MOFs with low toxicity, oxidative ability, and biocompatibility, which plays vital role in the application of this class of MOFs in medical field. Mn-MOFs show great potential in biomedical applications, and has been extensively studied as compared to other MOFs in transition metal series. They are important in medical applications because Mn(II) possess large electron spin number and longer electron relaxation time. They display fast water exchange rate and could be employed as a potential MRI contrast agent because of their strong targeting ability. Manganese complexes with different ligands also display prospective applications in area such as carrier for drug targeting in anti-tumor and antimicrobial therapy. In the review presented herewith, the application of Mn-based complexes and Mn-MOFs have been emphasized in the area such as imaging viz. MRI, multimodal imaging, antitumor activities such as chemodynamic therapy, photodynamic therapy, sonodynamic therapy and antimicrobial applications. Also, how rational designing and syntheses of targeted Mn-based complexes and Mn-MOFs can engender desired applications.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Maggie发布了新的文献求助30
刚刚
自觉亦绿发布了新的文献求助10
2秒前
lhw完成签到,获得积分10
3秒前
cui发布了新的文献求助10
4秒前
4秒前
科研通AI2S应助waq采纳,获得10
4秒前
min完成签到 ,获得积分10
5秒前
领导范儿应助麋鹿采纳,获得10
5秒前
Jasper应助自信惋清采纳,获得10
6秒前
卫东完成签到,获得积分0
6秒前
活力的母鸡完成签到,获得积分10
7秒前
慕青应助谢昱采纳,获得10
7秒前
咕噜完成签到,获得积分20
7秒前
科研通AI2S应助swy采纳,获得10
7秒前
jevon应助小鱼儿飞飞采纳,获得10
8秒前
8秒前
9秒前
123669应助夏爽2023采纳,获得10
9秒前
卫东发布了新的文献求助30
12秒前
烟花应助乌兰巴托没有海采纳,获得10
13秒前
ftdwccch发布了新的文献求助10
13秒前
专注的语堂完成签到,获得积分10
14秒前
14秒前
15秒前
科研通AI2S应助兜兜采纳,获得10
15秒前
淡淡的若冰应助且歌且行采纳,获得20
16秒前
16秒前
17秒前
一一应助sylvia采纳,获得30
18秒前
18秒前
英俊的铭应助专注的语堂采纳,获得10
18秒前
竞鹤发布了新的文献求助10
18秒前
yuting发布了新的文献求助100
19秒前
20秒前
李西瓜发布了新的文献求助10
20秒前
852应助nmr采纳,获得10
20秒前
21秒前
21秒前
自信惋清发布了新的文献求助10
22秒前
22秒前
高分求助中
歯科矯正学 第7版(或第5版) 1004
Semiconductor Process Reliability in Practice 1000
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
GROUP-THEORY AND POLARIZATION ALGEBRA 500
Mesopotamian divination texts : conversing with the gods : sources from the first millennium BCE 500
Days of Transition. The Parsi Death Rituals(2011) 500
The Heath Anthology of American Literature: Early Nineteenth Century 1800 - 1865 Vol. B 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3233417
求助须知:如何正确求助?哪些是违规求助? 2879936
关于积分的说明 8213289
捐赠科研通 2547370
什么是DOI,文献DOI怎么找? 1376892
科研通“疑难数据库(出版商)”最低求助积分说明 647713
邀请新用户注册赠送积分活动 623144