氨基酸
生物制药
活性成分
生化工程
化学
组合化学
计算机科学
生物化学
生物技术
医学
工程类
药理学
生物
作者
Agustina Bongioanni,María Soledad Bueno,Belén Alejandra Mezzano,Marcela R. Longhi,Claudia Garnero
标识
DOI:10.1016/j.ijpharm.2021.121375
摘要
Amino acids are natural compounds that can be safely used in pharmaceutical applications. Considering the great interest in the amino acids used in the pharmaceutical industry, this article presents an overview of investigations reported in recent years. In this regard, the first sections begin with an introductory description of the properties, classification and safety of amino acids, while in the other sections the most common methods for the preparation of amino acids formulations and their application on solubilization, permeation and stabilization of several active pharmaceutical ingredients are described. Furthermore, available data about the multicomponent systems approach is included. Lastly, the impact of amino acids formulations on therapeutic efficacy is explored. The advantages illustrated suggest that amino acids are capable of improving the biopharmaceutical properties of drugs.
科研通智能强力驱动
Strongly Powered by AbleSci AI