血小板生成素
巨核细胞
细胞生物学
血小板生成素
蛋白激酶B
化学
血小板
癌症研究
生物
信号转导
免疫学
造血
干细胞
作者
Shilei Chen,Mengjia Hu,Mingqiang Shen,Song Wang,Cheng Wang,Fang Chen,Yong Tang,Xinmiao Wang,Hao Zeng,Mo Chen,Jining Gao,FengChao Wang,Yongping Su,Yang Xu
出处
期刊:Blood
[American Society of Hematology]
日期:2018-07-12
卷期号:132 (2): 210-222
被引量:31
标识
DOI:10.1182/blood-2018-01-825927
摘要
Key Points IGF-1 has the ability to promote megakaryocyte differentiation, PPF, and platelet release. The effect of IGF-1 on thrombopoiesis is mediated primarily by AKT activation with the assistance of SRC-3.
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