Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation
药代动力学
CYP3A4型
药理学
医学
细胞色素P450
内科学
新陈代谢
作者
Nageshwar Budha,Tao Ji,Luna Musib,Steve Eppler,Mark J. Dresser,Yuan Chen,Jin Y. Jin