Anti‐PD‐L1 DNAzyme Loaded Photothermal Mn2+/Fe3+ Hybrid Metal‐Phenolic Networks for Cyclically Amplified Tumor Ferroptosis‐Immunotherapy (Adv. Healthcare Mater. 8/2022)

Advanced Healthcare MaterialsVolume 11, Issue 8 2270044 Back CoverFree Access Anti-PD-L1 DNAzyme Loaded Photothermal Mn2+/Fe3+ Hybrid Metal-Phenolic Networks for Cyclically Amplified Tumor Ferroptosis-Immunotherapy (Adv. Healthcare Mater. 8/2022) Peng Liu, Peng LiuSearch for more papers by this authorXinyi Shi, Xinyi ShiSearch for more papers by this authorYing Peng, Ying PengSearch for more papers by this authorJianming Hu, Jianming HuSearch for more papers by this authorJinsong Ding, Jinsong DingSearch for more papers by this authorWenhu Zhou, Wenhu ZhouSearch for more papers by this author Peng Liu, Peng LiuSearch for more papers by this authorXinyi Shi, Xinyi ShiSearch for more papers by this authorYing Peng, Ying PengSearch for more papers by this authorJianming Hu, Jianming HuSearch for more papers by this authorJinsong Ding, Jinsong DingSearch for more papers by this authorWenhu Zhou, Wenhu ZhouSearch for more papers by this author First published: 20 April 2022 https://doi.org/10.1002/adhm.202270044AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Tumor Therapy In article number 2102315 by Wenhu Zhou and co-workers, a metal-phenolic network (MPN) nanoplatform with all-active components is constructed via coordination between tannic acid (TA) and metal ion complex of Fe3+/Mn2+, through which a PD-L1 inhibiting DNAzyme (DZ) is loaded. With external laser irradiation, PTT is initiated to synergize with ferroptosis for enhanced ICD, and the combination of DZ-mediated PD-L1 suppression results in a cyclically amplified tumor ferroptosis-immunotherapy. Volume11, Issue8April 20, 20222270044 RelatedInformation