Optimizing phenyl selenide-based BODIPYs as fluorescent probes for diagnosing cancer and drug-induced liver injury via cysteine

By optimizing phenyl selenide-based BODIPYs, probe BDP-Se-MOS for detecting Cys was obtained. It could not only discriminate between normal and cancer cells, but also image Cys in tumor-bearing mice as well as the fluctuations of Cys in DILI model.