组内相关
医学
接收机工作特性
偏斜
判别式
统计
公式-5D
相关性
相关系数
人口学
抗逆转录病毒疗法
人类免疫缺陷病毒(HIV)
心理测量学
健康相关生活质量
内科学
数学
临床心理学
家庭医学
几何学
疾病
人工智能
社会学
计算机科学
病毒载量
作者
Xiaowen Wang,Hongbing Luo,Enlong Yao,Renhai Tang,Wenbing Dong,Fuyong Liu,Jun Liang,Minyang Xiao,Zuyang Zhang,Jin Niu,Lijun Song,Liru Fu,Xuehua Li,Shicong Qian,Qing Guo,Zhizhong Song
出处
期刊:Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2022-11-11
卷期号:101 (45): e31666-e31666
标识
DOI:10.1097/md.0000000000031666
摘要
We compared the discriminative validity, agreement and sensitivity of EQ-5D-5L and SF-6D utility scores in people living with HIV/AIDS (PLWHIV). We conducted a cross-sectional survey among PLWHIV aged more than 18 years old in 9 municipalities in Yunnan Province, China. A convenience sample was enrolled. We administered the SF-12 and EQ-5D-5L to measure health-related quality of life. The utility index of the SF-6D was derived from the SF-12. We calculate correlation coefficients to evaluate the relationship and agreement of 2 instruments. To evaluate the homogeneity of the EQ-5D-5L and SF-6D, intraclass correlation coefficients, scatter plots, and Bland-Altman plots were computed and drawn. We also used receiver operating characteristic curves to compare the discriminative properties and sensitivity of the econometric index. A total of 1797 respondents, with a mean age of 45.6 ± 11.7 years, was interviewed. The distribution of EQ-5D-5L scores skewed towards full health with a skewness of -3.316. The overall correlation between EQ-5D-5L and SF-6D index scores was 0.46 (P < .001). The association of the 2 scales appeared stronger at the upper end. An intraclass correlation coefficient of 0.59 between the EQ-5D-5L and SF-6D meant a moderate correlation and indicated general agreement. The Bland-Altman plot displayed the same results as the scatter plot. The receiver operating characteristic curve showed that the AUC for the SF-6D was 0.776 (95% CI: 0.757, 0.796) and that for the EQ-5D-5L was 0.732 (95% CI: 0.712, 0.752) by the PCS-12, and it was 0.782 (95% CI: 0.763, 0.802) for the SF-6D and 0.690 (95% CI: 0.669, 0.711) for the EQ-5D-5L by the MCS-12. Our study demonstrated evidence of the performance of EQ-5D-5L and SF-6D index scores to measure health utility in people living with HIV/AIDS. There were significant differences in their performance. We preferred to apply the SF-6D to measure the health utility of PLWHIV during the combined antiretroviral therapy period. Our study has demonstrated evidence for instrument choice and preference measurements in PLWHIV under combined antiretroviral therapy.
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