Risk factors of dementia in type 2 diabetes mellitus: The Hong Kong diabetes study

This population-based cohort study investigated the risk factors of incident dementia and vascular dementia in type 2 diabetic patients (≥45 years old) attending the Hong Kong Hospital Authority between 1st January and 31st December 2009.Of the 273876 patients included,9994 showed incident dementia (median follow-up: 4245 days). Multivariable Cox regression identified older age (HR: 1.09 [95% CI: 1.08-1.10]) and antiplatelet use (HR: 1.36 [1.14-1.62]) as risk factors for incident dementia, and older age (HR: 1.07 [1.06-1.08]), ischemic stroke (HR: 1.47 [1.09-1.98]), fasting blood glucose (HR: 1.10 [1.01-1.20]), antiplatelets (HR: 1.92 [1.51-2.44]), and calcium channel blocker (HR: 1.28 [1.04-1.57]) use as risk factors of incident vascular dementia.