Staphylococcus Aureus Skin Colonization Promotes Food Anaphylaxis In Epicutaneously Sensitized Mice

The skin of atopic dermatitis (AD) patients is often colonized by S. aureus strains that produce superantigens (SAg), primarily staphylococcal enterotoxin B (SEB). There is a positive association between S. aureus skin colonization and food allergy in AD. We dissected its mechanisms using a mouse model of AD elicited by epicutaneous (EC) sensitization with antigen.