Characteristics of Global Radiation Therapy Trials Between 2017 and 2022: A Cross-Sectional Study

Radiation therapy is a critical component of effective treatment and control for nearly every cancer. 1 Atun R Jaffray DA Barton MB et al. Expanding global access to radiotherapy. Lancet Oncol. 2015; 16: 1153-1186 Abstract Full Text Full Text PDF PubMed Scopus (592) Google Scholar As many as half of patients with cancer would receive and benefit from radiation therapy during their course of disease for disease eradication, local control, or palliation. 1 Atun R Jaffray DA Barton MB et al. Expanding global access to radiotherapy. Lancet Oncol. 2015; 16: 1153-1186 Abstract Full Text Full Text PDF PubMed Scopus (592) Google Scholar ,2 Hanna T Shafiq J Delaney G et al. The population benefit of evidence-based radiotherapy: 5-year local control and overall survival benefits. Radiother Oncol. 2018; 126: 191-197 Abstract Full Text Full Text PDF PubMed Scopus (54) Google Scholar Over the past decades, many important advances in radiation therapy have emerged, including intensity modulated radiation therapy, stereotactic ablative radiation therapy, tomotherapy, and particle-beam radiation therapy. 3 Citrin DE. Recent developments in radiotherapy. N Engl J Med. 2017; 377: 1065-1075 Crossref PubMed Scopus (248) Google Scholar ,4 Fiorino C Guckenberger M Schwarz M et al. Technology-driven research for radiotherapy innovation. Mol Oncol. 2020; 14: 1500-1513 Crossref PubMed Scopus (45) Google Scholar These modern radiation therapy technologies provide patients with more effective and safer treatment.