化学
等电聚焦
地中海贫血
糖尿病
色谱法
内科学
生物化学
内分泌学
医学
酶
作者
Hao Fu,Youli Tian,Genhan Zha,Xuan Xiao,Hengying Zhu,Qiang Zhang,Chunyan Yu,Wei Sun,Chang Ming Li,Wei Li,Ping Chen,Chengxi Cao
标识
DOI:10.1016/j.aca.2024.342696
摘要
Hemoglobin (Hb) is an important protein in red blood cells and a crucial diagnostic indicator of diseases, e.g., diabetes, thalassemia, and anemia. However, there is a rare report on methods for the simultaneous screening of diabetes, anemia, and thalassemia. Isoelectric focusing (IEF) is a common separative tool for the separation and analysis of Hb. However, the current analysis of IEF images is time-consuming and cannot be used for simultaneous screening. Therefore, an artificial intelligence (AI) of IEF image recognition is desirable for accurate, sensitive, and low-cost screening.
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