Solvent-free and Catalyst-free Reaction of o-Amino Benzophenone with Aryl Isothiocyanates: Expedient Access to Congested 4-Phenyl-4-Hydroxyquinazolin-2-thione Derivatives

An efficient method to construct congested 4-phenyl-4-hydroxyquinazolin-2-thiones 3 via solvent-free and catalyst-free addition of aryl isothiocyanates 2 and with o-aminobenzophenone 1 under thermal conditions to provide new congested 4-phenyl-4-hydroxyquinazolin-2-thiones 3...