Tissue-specific inducible IL-33 expression elicits features of eosinophilic esophagitis
嗜酸性食管炎
表达式(计算机科学)
医学
病理
嗜酸性
免疫学
计算机科学
疾病
程序设计语言
作者
Grace C. Pyon,Mia Y. Masuda,Arina Putikova,Huijun Luo,Jessica B. Gibson,Amy Dao,Diana Ortiz,Piper L Heiligenstein,James J Bonellos,William E. LeSuer,Rish K. Pai,Shipra Garg,Matthew A. Rank,Hiroshi Nakagawa,Hirohito Kita,Benjamin L. Wright,Alfred D. Doyle
IL-33 is a type 2 inflammatory cytokine that is elevated in the esophageal epithelium of EoE subjects. We previously developed a mouse model of EoE dependent on constitutive overexpression of IL-33 from the esophageal epithelium (EoE33).