Progress in Fluorescent Probes for Carbon Monoxide Detecting

As an important endogenous gas transmitter, carbon monoxide (CO) has been found taking part in multiple physiological and pathological processes for life.Therefore, the selective recognition and sensitive detection of CO are of great biological and medical significance.Fluorescent probe method is highlighted by its good selectivity, high sensitivity, suitable for high-throughput screening, especially noninvasive detection, and real-time monitoring in situ.Therefore, the development of fluorescent probes for intracellular CO has been becoming one of the hot topics.Herein, the progress during the last decade of fluorescent molecular probes based on the small molecules for CO detection is reviewed.These fluorescent probes are classified and concluded according to the design concepts, detection mechanism, and biological applications.In addition, the relationship between molecular structures and properties is elucidated.Finally, the challenge and application prospects for the development of CO fluorescent probes are also discussed.