High-Resolution Holographic Microscopy Exploiting Speckle-Correlation Scattering Matrix

High-resolution imaging at long working distances is very important in optical microscopy, providing great freedom in sample and imaging conditions. However, this is challenging for a conventional refraction-based optical lens, due to optical aberrations. The authors propose a microscopic technique based on multiple scattering of light instead of refractive optics, where the complex amplitude of light is retrieved using a scattering layer. This approach will impact engineering solutions for high-resolution long-working-distance imaging in optical microscopy, and can be extended to holography for $e.g.$ particle tracking or cell pathology.