Lysozyme: an important defence molecule of fish innate immune system

Aquaculture ResearchVolume 39, Issue 3 p. 223-239 Lysozyme: an important defence molecule of fish innate immune system Shailesh Saurabh, Shailesh Saurabh Fish Health Management Division, Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, IndiaSearch for more papers by this authorP K Sahoo, P K Sahoo Fish Health Management Division, Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, IndiaSearch for more papers by this author Shailesh Saurabh, Shailesh Saurabh Fish Health Management Division, Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, IndiaSearch for more papers by this authorP K Sahoo, P K Sahoo Fish Health Management Division, Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar, IndiaSearch for more papers by this author First published: 24 January 2008 https://doi.org/10.1111/j.1365-2109.2007.01883.xCitations: 942 Correspondence: P K Sahoo, Fish Health Management Division, Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar 751 002, India. E-mail: pksahoo1@hotmail.com Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract The innate immune system of fish is considered to be the first line of defence against a broad spectrum of pathogens and is more important for fish as compared with mammals. Lysozyme level or activity is an important index of innate immunity of fish and is ubiquitous in its distribution among living organisms. It is well documented that fish lysozyme possess lytic activity against both Gram-positive bacteria and Gram-negative bacteria. It is also known to be opsonic in nature and activates the complement system and phagocytes. It is present in mucus, lymphoid tissue, plasma and other body fluids of freshwater and marine fish. It is also expressed in a wide variety of tissues. Lysozyme activity has been shown to vary depending on the sex, age and size, season, water temperature, pH, toxicants, infections and degree of stressors. Here, we review our current understanding of different types of lysozyme and their expression and its role in fish innate immune system. Citing Literature Volume39, Issue3February 2008Pages 223-239 RelatedInformation