脑脊液
脑脊液漏
泄漏
听力损失
医学
内耳
病因学
复合肌肉动作电位
豚鼠
麻醉
解剖
电生理学
听力学
内科学
环境工程
工程类
作者
A Walsted,Per J. Nilsson,Jens Gerlif
出处
期刊:Audiology and Neuro-otology
[S. Karger AG]
日期:1996-01-01
卷期号:1 (5): 256-264
被引量:12
摘要
Hearing loss has been reported following leakage of cerebrospinal fluid (CSF). The etiology has been attributed to an induced imbalance in the intracochlear hydrodynamics. The present study reports a guinea pig model with surgically induced loss of CSF. In 18 anesthetized animals, CSF was drained by a suboccipital incision in the dura. Eighteen animals were used as controls. The compound action potentials were recorded by an ear canal silver electrode. The animals with CSF loss showed a small increase in threshold and latency, while the control group was unchanged. The concept of an induced inner ear fluid dysfunction after CSF leak is supported by these findings.
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